ChloroquineV1, an2020, Analysis, bibRecord, 000123

LZAP promotes the proliferation and invasiveness of cervical carcinoma cells by targeting AKT and EMT

Identifieur interne : 000123 ( an2020/Analysis ); précédent : 000122; suivant : 000124

LZAP promotes the proliferation and invasiveness of cervical carcinoma cells by targeting AKT and EMT

Source :

Journal of Cancer [ 1837-9664 ] ; 2020.

RBID : PMC:6995386

Abstract

Objective: To explore the relationship and mechanism of LZAP in the occurrence and development of cervical cancer and to provide a new target and intervention method for the treatment of cervical cancer.

Methods: Data mining and analysis of LZAP expression levels were performed using several online databases, including The Cancer Genome Atlas (TCGA). A cervical cancer cell line that stably overexpresses LZAP was established, and the effect of LZAP overexpression on cell proliferation, invasion, migration and tumor formation in vivo as well as its mechanism were explored.

Results: Our study shows that the expression of LZAP is upregulated in cervical cancer. The overexpression of LZAP can significantly promote the proliferation, colony formation, and invasion and migration abilities of cervical cancer cells. The tumorigenesis test in nude mice showed that overexpression of LZAP could promote the tumorigenicity of cervical cancer cells in vivo. LZAP could also promote the phosphorylation of AKT at position 473 and the epithelial-mesenchymal transition (EMT).

Conclusion: The expression of LAZP is increased in cervical cancer, which can enhance the invasion, metastasis, and EMT in cervical cancer cells by promoting AKT phosphorylation.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995386

DOI: 10.7150/jca.39359
PubMed: 32047568
PubMed Central: 6995386

Affiliations:

Links to Exploration step

PMC:6995386

Le document en format XML

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<author><name sortKey="Dai, Yi Fang" sort="Dai, Yi Fang" uniqKey="Dai Y" first="Yi-Fang" last="Dai">Yi-Fang Dai</name>
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<author><name sortKey="Guo, Dan Hua" sort="Guo, Dan Hua" uniqKey="Guo D" first="Dan-Hua" last="Guo">Dan-Hua Guo</name>
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<affiliation wicri:level="1"><nlm:aff id="A2">Fujian Provincial Key Laboratory for Prenatal diagnosis and Birth Defect, Fuzhou 350001, China</nlm:aff>
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<author><name sortKey="Li, Ying" sort="Li, Ying" uniqKey="Li Y" first="Ying" last="Li">Ying Li</name>
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<wicri:regionArea>Center of Prenatal Diagnosis, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="A2">Fujian Provincial Key Laboratory for Prenatal diagnosis and Birth Defect, Fuzhou 350001, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
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<author><name sortKey="Huang, Hai Long" sort="Huang, Hai Long" uniqKey="Huang H" first="Hai-Long" last="Huang">Hai-Long Huang</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Center of Prenatal Diagnosis, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Center of Prenatal Diagnosis, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="A2">Fujian Provincial Key Laboratory for Prenatal diagnosis and Birth Defect, Fuzhou 350001, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Fujian Provincial Key Laboratory for Prenatal diagnosis and Birth Defect, Fuzhou 350001</wicri:regionArea>
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<author><name sortKey="Zheng, Xiang Qing" sort="Zheng, Xiang Qing" uniqKey="Zheng X" first="Xiang-Qing" last="Zheng">Xiang-Qing Zheng</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Gynecology, Fujian Provincial Maternity and Children's Hospital, Fuzhou 350001</wicri:regionArea>
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</author>
<author><name sortKey="Xu, Liang Pu" sort="Xu, Liang Pu" uniqKey="Xu L" first="Liang-Pu" last="Xu">Liang-Pu Xu</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Center of Prenatal Diagnosis, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Center of Prenatal Diagnosis, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001</wicri:regionArea>
<placeName><settlement type="city">Fuzhou</settlement>
<region type="province">Fujian</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Fujian Provincial Key Laboratory for Prenatal diagnosis and Birth Defect, Fuzhou 350001, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Fujian Provincial Key Laboratory for Prenatal diagnosis and Birth Defect, Fuzhou 350001</wicri:regionArea>
<placeName><settlement type="city">Fuzhou</settlement>
<region type="province">Fujian</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Cancer</title>
<idno type="eISSN">1837-9664</idno>
<imprint><date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><bold>Objective</bold>
: To explore the relationship and mechanism of LZAP in the occurrence and development of cervical cancer and to provide a new target and intervention method for the treatment of cervical cancer.</p>
<p><bold>Methods</bold>
: Data mining and analysis of LZAP expression levels were performed using several online databases, including The Cancer Genome Atlas (TCGA). A cervical cancer cell line that stably overexpresses LZAP was established, and the effect of LZAP overexpression on cell proliferation, invasion, migration and tumor formation in vivo as well as its mechanism were explored.</p>
<p><bold>Results</bold>
: Our study shows that the expression of LZAP is upregulated in cervical cancer. The overexpression of LZAP can significantly promote the proliferation, colony formation, and invasion and migration abilities of cervical cancer cells. The tumorigenesis test in nude mice showed that overexpression of LZAP could promote the tumorigenicity of cervical cancer cells in vivo. LZAP could also promote the phosphorylation of AKT at position 473 and the epithelial-mesenchymal transition (EMT).</p>
<p><bold>Conclusion</bold>
: The expression of LAZP is increased in cervical cancer, which can enhance the invasion, metastasis, and EMT in cervical cancer cells by promoting AKT phosphorylation.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Ferlay, J" uniqKey="Ferlay J">J Ferlay</name>
</author>
<author><name sortKey="Soerjomataram, I" uniqKey="Soerjomataram I">I Soerjomataram</name>
</author>
<author><name sortKey="Dikshit, R" uniqKey="Dikshit R">R Dikshit</name>
</author>
<author><name sortKey="Eser, S" uniqKey="Eser S">S Eser</name>
</author>
<author><name sortKey="Mathers, C" uniqKey="Mathers C">C Mathers</name>
</author>
<author><name sortKey="Rebelo, M" uniqKey="Rebelo M">M Rebelo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Peralta Zaragoza, O" uniqKey="Peralta Zaragoza O">O Peralta-Zaragoza</name>
</author>
<author><name sortKey="Deas, J" uniqKey="Deas J">J Deas</name>
</author>
<author><name sortKey="Meneses Acosta, A" uniqKey="Meneses Acosta A">A Meneses-Acosta</name>
</author>
<author><name sortKey="De La, Ogf" uniqKey="De La O">OGF De la</name>
</author>
<author><name sortKey="Fernandez Tilapa, G" uniqKey="Fernandez Tilapa G">G Fernandez-Tilapa</name>
</author>
<author><name sortKey="Gomez Ceron, C" uniqKey="Gomez Ceron C">C Gomez-Ceron</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ferlay, J" uniqKey="Ferlay J">J Ferlay</name>
</author>
<author><name sortKey="Shin, Hr" uniqKey="Shin H">HR Shin</name>
</author>
<author><name sortKey="Bray, F" uniqKey="Bray F">F Bray</name>
</author>
<author><name sortKey="Forman, D" uniqKey="Forman D">D Forman</name>
</author>
<author><name sortKey="Mathers, C" uniqKey="Mathers C">C Mathers</name>
</author>
<author><name sortKey="Parkin, Dm" uniqKey="Parkin D">DM Parkin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Srivastava, An" uniqKey="Srivastava A">AN Srivastava</name>
</author>
<author><name sortKey="Misra, Js" uniqKey="Misra J">JS Misra</name>
</author>
<author><name sortKey="Srivastava, S" uniqKey="Srivastava S">S Srivastava</name>
</author>
<author><name sortKey="Das, Bc" uniqKey="Das B">BC Das</name>
</author>
<author><name sortKey="Gupta, S" uniqKey="Gupta S">S Gupta</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kuo, Cy" uniqKey="Kuo C">CY Kuo</name>
</author>
<author><name sortKey="Schelz, Z" uniqKey="Schelz Z">Z Schelz</name>
</author>
<author><name sortKey="Toth, B" uniqKey="Toth B">B Toth</name>
</author>
<author><name sortKey="Vasas, A" uniqKey="Vasas A">A Vasas</name>
</author>
<author><name sortKey="Ocsovszki, I" uniqKey="Ocsovszki I">I Ocsovszki</name>
</author>
<author><name sortKey="Chang, Fr" uniqKey="Chang F">FR Chang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Ching, Yp" uniqKey="Ching Y">YP Ching</name>
</author>
<author><name sortKey="Lam, Wh" uniqKey="Lam W">WH Lam</name>
</author>
<author><name sortKey="Qi, Z" uniqKey="Qi Z">Z Qi</name>
</author>
<author><name sortKey="Zhang, M" uniqKey="Zhang M">M Zhang</name>
</author>
<author><name sortKey="Wang, Jh" uniqKey="Wang J">JH Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wamsley, Jj" uniqKey="Wamsley J">JJ Wamsley</name>
</author>
<author><name sortKey="Gary, C" uniqKey="Gary C">C Gary</name>
</author>
<author><name sortKey="Biktasova, A" uniqKey="Biktasova A">A Biktasova</name>
</author>
<author><name sortKey="Hajek, M" uniqKey="Hajek M">M Hajek</name>
</author>
<author><name sortKey="Bellinger, G" uniqKey="Bellinger G">G Bellinger</name>
</author>
<author><name sortKey="Virk, R" uniqKey="Virk R">R Virk</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name>
</author>
<author><name sortKey="Jiang, H" uniqKey="Jiang H">H Jiang</name>
</author>
<author><name sortKey="Luo, S" uniqKey="Luo S">S Luo</name>
</author>
<author><name sortKey="Zhang, M" uniqKey="Zhang M">M Zhang</name>
</author>
<author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name>
</author>
<author><name sortKey="Sun, F" uniqKey="Sun F">F Sun</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liu, Q" uniqKey="Liu Q">Q Liu</name>
</author>
<author><name sortKey="Luo, Xy" uniqKey="Luo X">XY Luo</name>
</author>
<author><name sortKey="Jiang, H" uniqKey="Jiang H">H Jiang</name>
</author>
<author><name sortKey="Yang, Mh" uniqKey="Yang M">MH Yang</name>
</author>
<author><name sortKey="Yuan, Gh" uniqKey="Yuan G">GH Yuan</name>
</author>
<author><name sortKey="Tang, Z" uniqKey="Tang Z">Z Tang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mak, Gw" uniqKey="Mak G">GW Mak</name>
</author>
<author><name sortKey="Chan, Mm" uniqKey="Chan M">MM Chan</name>
</author>
<author><name sortKey="Leong, Vy" uniqKey="Leong V">VY Leong</name>
</author>
<author><name sortKey="Lee, Jm" uniqKey="Lee J">JM Lee</name>
</author>
<author><name sortKey="Yau, To" uniqKey="Yau T">TO Yau</name>
</author>
<author><name sortKey="Ng, Io" uniqKey="Ng I">IO Ng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stav, D" uniqKey="Stav D">D Stav</name>
</author>
<author><name sortKey="Bar, I" uniqKey="Bar I">I Bar</name>
</author>
<author><name sortKey="Sandbank, J" uniqKey="Sandbank J">J Sandbank</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name>
</author>
<author><name sortKey="An, H" uniqKey="An H">H An</name>
</author>
<author><name sortKey="Mayo, Mw" uniqKey="Mayo M">MW Mayo</name>
</author>
<author><name sortKey="Baldwin, As" uniqKey="Baldwin A">AS Baldwin</name>
</author>
<author><name sortKey="Yarbrough, Wg" uniqKey="Yarbrough W">WG Yarbrough</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tapia, O" uniqKey="Tapia O">O Tapia</name>
</author>
<author><name sortKey="Riquelme, I" uniqKey="Riquelme I">I Riquelme</name>
</author>
<author><name sortKey="Leal, P" uniqKey="Leal P">P Leal</name>
</author>
<author><name sortKey="Sandoval, A" uniqKey="Sandoval A">A Sandoval</name>
</author>
<author><name sortKey="Aedo, S" uniqKey="Aedo S">S Aedo</name>
</author>
<author><name sortKey="Weber, H" uniqKey="Weber H">H Weber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jiang, H" uniqKey="Jiang H">H Jiang</name>
</author>
<author><name sortKey="Luo, S" uniqKey="Luo S">S Luo</name>
</author>
<author><name sortKey="Li, H" uniqKey="Li H">H Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Engelman, Ja" uniqKey="Engelman J">JA Engelman</name>
</author>
<author><name sortKey="Luo, J" uniqKey="Luo J">J Luo</name>
</author>
<author><name sortKey="Cantley, Lc" uniqKey="Cantley L">LC Cantley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barber, Ag" uniqKey="Barber A">AG Barber</name>
</author>
<author><name sortKey="Castillo Rtin, M" uniqKey="Castillo Rtin M">M Castillo㎝artin</name>
</author>
<author><name sortKey="Bonal, Dm" uniqKey="Bonal D">DM Bonal</name>
</author>
<author><name sortKey="Jia, Aj" uniqKey="Jia A">AJ Jia</name>
</author>
<author><name sortKey="Cordon Rdo, C" uniqKey="Cordon Rdo C">C Cordon〤ardo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vincent Salomon, A" uniqKey="Vincent Salomon A">A Vincent-Salomon</name>
</author>
<author><name sortKey="Thiery, Jp" uniqKey="Thiery J">JP Thiery</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cardiff, D" uniqKey="Cardiff D">D Cardiff</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Handschuh, G" uniqKey="Handschuh G">G Handschuh</name>
</author>
<author><name sortKey="Candidus, S" uniqKey="Candidus S">S Candidus</name>
</author>
<author><name sortKey="Luber, B" uniqKey="Luber B">B Luber</name>
</author>
<author><name sortKey="Reich, U" uniqKey="Reich U">U Reich</name>
</author>
<author><name sortKey="Schott, C" uniqKey="Schott C">C Schott</name>
</author>
<author><name sortKey="Oswald, S" uniqKey="Oswald S">S Oswald</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bremnes, Rm" uniqKey="Bremnes R">RM Bremnes</name>
</author>
<author><name sortKey="Veve, R" uniqKey="Veve R">R Veve</name>
</author>
<author><name sortKey="Gabrielson, E" uniqKey="Gabrielson E">E Gabrielson</name>
</author>
<author><name sortKey="Hirsch, Fr" uniqKey="Hirsch F">FR Hirsch</name>
</author>
<author><name sortKey="Baron, A" uniqKey="Baron A">A Baron</name>
</author>
<author><name sortKey="Bemis, L" uniqKey="Bemis L">L Bemis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wheelock, Mj" uniqKey="Wheelock M">MJ Wheelock</name>
</author>
<author><name sortKey="Shintani, Y" uniqKey="Shintani Y">Y Shintani</name>
</author>
<author><name sortKey="Maeda, M" uniqKey="Maeda M">M Maeda</name>
</author>
<author><name sortKey="Fukumoto, Y" uniqKey="Fukumoto Y">Y Fukumoto</name>
</author>
<author><name sortKey="Johnson, Kr" uniqKey="Johnson K">KR Johnson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhang, A" uniqKey="Zhang A">A Zhang</name>
</author>
<author><name sortKey="Chen, G" uniqKey="Chen G">G Chen</name>
</author>
<author><name sortKey="Meng, L" uniqKey="Meng L">L Meng</name>
</author>
<author><name sortKey="Wang, Q" uniqKey="Wang Q">Q Wang</name>
</author>
<author><name sortKey="Hu, W" uniqKey="Hu W">W Hu</name>
</author>
<author><name sortKey="Xi, L" uniqKey="Xi L">L Xi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wei, Y" uniqKey="Wei Y">Y Wei</name>
</author>
<author><name sortKey="Nhieu, Jtv" uniqKey="Nhieu J">JTV Nhieu</name>
</author>
<author><name sortKey="Prigent, S" uniqKey="Prigent S">S Prigent</name>
</author>
<author><name sortKey="Srivatanakul, P" uniqKey="Srivatanakul P">P Srivatanakul</name>
</author>
<author><name sortKey="Tiollais, P" uniqKey="Tiollais P">P Tiollais</name>
</author>
<author><name sortKey="Buendia, Ma" uniqKey="Buendia M">MA Buendia</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name>
</author>
<author><name sortKey="Yin, J" uniqKey="Yin J">J Yin</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Shao, M" uniqKey="Shao M">M Shao</name>
</author>
<author><name sortKey="Duan, F" uniqKey="Duan F">F Duan</name>
</author>
<author><name sortKey="Wu, W" uniqKey="Wu W">W Wu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mccubrey, Ja" uniqKey="Mccubrey J">JA McCubrey</name>
</author>
<author><name sortKey="Steelman, Ls" uniqKey="Steelman L">LS Steelman</name>
</author>
<author><name sortKey="Abrams, Sl" uniqKey="Abrams S">SL Abrams</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
<region><li>Fujian</li>
</region>
<settlement><li>Fuzhou</li>
</settlement>
</list>
<tree><country name="République populaire de Chine"><region name="Fujian"><name sortKey="Dai, Yi Fang" sort="Dai, Yi Fang" uniqKey="Dai Y" first="Yi-Fang" last="Dai">Yi-Fang Dai</name>
</region>
<name sortKey="Dai, Yi Fang" sort="Dai, Yi Fang" uniqKey="Dai Y" first="Yi-Fang" last="Dai">Yi-Fang Dai</name>
<name sortKey="Guo, Dan Hua" sort="Guo, Dan Hua" uniqKey="Guo D" first="Dan-Hua" last="Guo">Dan-Hua Guo</name>
<name sortKey="Guo, Dan Hua" sort="Guo, Dan Hua" uniqKey="Guo D" first="Dan-Hua" last="Guo">Dan-Hua Guo</name>
<name sortKey="He, De Qin" sort="He, De Qin" uniqKey="He D" first="De-Qin" last="He">De-Qin He</name>
<name sortKey="He, De Qin" sort="He, De Qin" uniqKey="He D" first="De-Qin" last="He">De-Qin He</name>
<name sortKey="He, Shu Qiong" sort="He, Shu Qiong" uniqKey="He S" first="Shu-Qiong" last="He">Shu-Qiong He</name>
<name sortKey="He, Shu Qiong" sort="He, Shu Qiong" uniqKey="He S" first="Shu-Qiong" last="He">Shu-Qiong He</name>
<name sortKey="Huang, Hai Long" sort="Huang, Hai Long" uniqKey="Huang H" first="Hai-Long" last="Huang">Hai-Long Huang</name>
<name sortKey="Huang, Hai Long" sort="Huang, Hai Long" uniqKey="Huang H" first="Hai-Long" last="Huang">Hai-Long Huang</name>
<name sortKey="Li, Ying" sort="Li, Ying" uniqKey="Li Y" first="Ying" last="Li">Ying Li</name>
<name sortKey="Li, Ying" sort="Li, Ying" uniqKey="Li Y" first="Ying" last="Li">Ying Li</name>
<name sortKey="Lin, Na" sort="Lin, Na" uniqKey="Lin N" first="Na" last="Lin">Na Lin</name>
<name sortKey="Lin, Na" sort="Lin, Na" uniqKey="Lin N" first="Na" last="Lin">Na Lin</name>
<name sortKey="Xu, Liang Pu" sort="Xu, Liang Pu" uniqKey="Xu L" first="Liang-Pu" last="Xu">Liang-Pu Xu</name>
<name sortKey="Xu, Liang Pu" sort="Xu, Liang Pu" uniqKey="Xu L" first="Liang-Pu" last="Xu">Liang-Pu Xu</name>
<name sortKey="Xu, Mu" sort="Xu, Mu" uniqKey="Xu M" first="Mu" last="Xu">Mu Xu</name>
<name sortKey="Zheng, Xiang Qing" sort="Zheng, Xiang Qing" uniqKey="Zheng X" first="Xiang-Qing" last="Zheng">Xiang-Qing Zheng</name>
<name sortKey="Zhong, Li Ying" sort="Zhong, Li Ying" uniqKey="Zhong L" first="Li-Ying" last="Zhong">Li-Ying Zhong</name>
</country>
</tree>
</affiliations>
</record>

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LZAP promotes the proliferation and invasiveness of cervical carcinoma cells by targeting AKT and EMT

LZAP promotes the proliferation and invasiveness of cervical carcinoma cells by targeting AKT and EMT

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